Dr. Irene De Francesco is a consultant clinical oncologist specializing in the treatment of skin cancer and colorectal cancer, with a special interest in anal squamous cell carcinoma (SCC). She has experience using advanced radiotherapy techniques, including VMAT, skin brachytherapy, and SABR (radiosurgery). Dr. De Francesco also has expertise in treating benign conditions with radiotherapy, including Dupuytren's Disease, Ledderhose Disease, and keloids. She completed her medical training at Sapienza University Medical School in Rome, Italy, and trained in clinical oncology at Sapienza University and The Royal Marsden. Her research focused on modern radiotherapy techniques and the assessment and improvement of treatment-related toxicity in anal cancer. She has been involved in the development of advanced imaging techniques and integrated single-photon emission computed tomography (SPECT) MRI systems for assessing treatment responses during and after chemo-radiotherapy. Dr. De Francesco continues to have a strong interest in research and clinical trials, particularly those involving the use of radiotherapy and systemic treatment in skin cancers and advanced radiotherapy techniques for anal cancer treatment.