Venesection therapy
A treatment for haemochromatosis and other conditions associated with too much iron or too many red blood cells
What is haemochromatosis?
It can cause fatigue, and may even damage your joints, liver, pancreas or heart.
A venesection can help lower iron levels, or treat polycythaemia vera (too many red blood cells).
Need to know
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What happens during treatment? icon plus
During a venesection, your nurse will remove a quantity of blood which will lower your iron levels and red cell count. It's similar to the procedure for donating blood and will be carried out as an outpatient appointment.
First, your nurse will check your blood pressure and clean an area on your arm, before inserting a needle into a vein. They'll remove approximately half a litre of blood. It's not uncommon to feel lightheaded or faint, which is nothing to worry about.
The procedure should take around 30 minutes, and your entire appointment will usually take around an hour. -
How to prepare icon plus
Before you have a venesection, your consultant or specialist nurse will explain the procedure to you. They'll probably recommend eating as normal beforehand, as this will help minimise any feeling of dizziness or lightheadedness during or after the venesection.
It's also important to drink between 2-3 litres of water at least 24 hours before. -
After treatment icon plus
You'll be offered something to drink after your venesection, and your blood pressure will be checked again. If you feel lightheaded you can lie down to recover. It's sensible to avoid driving immediately after a venesection, and we would advise you to rest for the remainder of the day.
Follow up venesections will be needed until your iron (ferritin) or red cell count is within normal range. Initially, you may need to repeat the procedure once every two weeks.
Over time, this could reduce to every 6 to 12 weeks. Regular bloods test (full blood count and iron/ferritin) will be done as per your consultant's recommendation to monitor your levels.
Our haemachromatosis specialists
Whilst a nurse will perform the venesection procedure in an outpatient setting, diagnosis and management of haemochromatosis is undertaken by an experienced gastroenterologist.
Your gastroenterologist will refer you for a venesection, when required, and will be able to answer any questions you may have prior to the procedure.




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