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Seronegative arthritis

Seronegative inflammatory arthritis

If a specific protein is found in your blood you may be diagnosed with this type of arthritis

About

Arthritis can be divided into two types, seropositive and seronegative. These refer to the presence in your blood of two proteins. Your type is determined by a blood test. One protein is called rheumatoid factor (RF) and the other is anti-CCP. Anti-CCP is more sensitive and may appear earlier. Seronegative arthritis affects a minority of cases.

Need to know

  • Symptoms of seronegative arthritis icon plus

    Symptoms may include: - painful and swollen joints - stiffness - tiredness
  • Diagnosis icon plus

    Your consultant will speak to you about your symptoms, discuss your medical history and perform a physical examination of your affected joints. To confirm a diagnosis they may ask you to carry out some, or all, of the following tests: - a blood test to check for two proteins (RF and anti-CCP) - X-ray, CT or MRI scans of the affected joints
  • Potential treatment options icon plus

    Treatment options include: - over-the-counter painkillers and non-steroidal anti-inflammatory drugs (NSAIDs) - disease-modifying anti-rheumatic drugs (DMARDs) - steroids - biologics (used for severe cases) - in severe cases, surgery may be recommended; possible procedures include hip, knee and ankle replacements
Consultant with patient

Our consultants

From complex surgery to straightforward procedures, we provide exceptional care across our network of hospitals, outpatient centres and specialist clinics.

Our facilities

From complex surgery to straightforward procedures, we provide exceptional care across our network of hospitals, outpatient centres and specialist clinics.

Request an appointment

We're happy to help you make an appointment with one of our experienced consultants.

This content is intended for general information only and does not replace the need for personal advice from a qualified health professional.
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