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Dr Jonathan Sive, Haematologist

Dr Jonathan Sive

PhD, MRCP, FRCPath

Consultant Haematologist

Fixed Price Packages

About

  • Biography icon plus

    Dr Jonathan Sive is a Consultant Haematologist at University College London Hospital (UCLH). He completed his specialist haematology training here, and subsequently carried out a PhD in Molecular Haematology at Cambridge University, using genomic technologies to study the mechanisms of leukaemia development.

    He has expertise in the diagnosis and management of blood cancers, specifically in the treatment of myeloma and other plasma cell disorders. He is also highly experienced in the investigation of anaemia and other abnormal blood counts.

    Dr Sive is a member of the British Society for Haematology (BSH), the UK Myeloma Forum and the UK Myeloma Research Alliance. He is currently the chair of the BSH guidelines group for the initial treatment of myeloma, and is actively engaged in a variety of clinical research projects. His work has been widely published in peer-reviewed articles and book chapters.

  • Clinical interests icon plus

    Myeloma, blood cancers, general haematology (including the investigation and management of anaemia, high and low white cell counts, neutropenia, high and low platelet counts, iron deficiency and paraproteins).
  • Publications icon plus

    Prevalence and timing of TP53 mutations in del(17p) myeloma and effect on survival. Chin M, Sive JI, Allen C, Roddie C, Chavda SJ, Smith D, Blombery P, Jones K, Ryland GL, Popat R, Rismani A, D'Sa S, Rabin N, Gale RE, Yong KL. Blood Cancer J. 2017 Sep 15;7(9):

    Genome-scale definition of the transcriptional programme associated with compromised PU.1 activity in acute myeloid leukaemia. Sive JI, Basilico S, Hannah R, Kinston SJ, Calero-Nieto FJ, Göttgens B. Leukemia. 2016 Jan;30(1):14-23.

    Global hypomethylation in myeloma is associated with poor prognosis. Sive JI, Feber A, Smith D, Quinn J, Beck S, Yong K. Br J Haematol. 2016 Feb;172(3):473-5.

    Transcriptional network control of normal and leukaemic haematopoiesis. Sive JI, Göttgens B.
    Exp Cell Res. 2014 Dec 10;329(2):255-64.

    Bivalent promoter marks and a latent enhancer may prime the leukaemia oncogene LMO1 for ectopic expression in T-cell leukaemia. Oram SH, Thoms J, Sive JI, Calero-Nieto FJ, Kinston SJ, Schütte J, Knezevic K, Lock RB, Pimanda JE, Göttgens B. Leukemia. 2013 Jun;27(6):1348-57.

    Adenoviremia has limited clinical impact in the majority of patients following alemtuzumab-based allogeneic stem cell transplantation in adults. Sive JI, Thomson KJ, Morris EC, Ward KN, Peggs KS.
    Clin Infect Dis. 2012 Nov 15;55(10):1362-70.

    Hotel-based ambulatory care for complex cancer patients: a review of the University College London Hospital experience. Sive J, Ardeshna KM, Cheesman S, le Grange F, Morris S, Nicholas C, Peggs K, Statham P, Goldstone AH. Leuk Lymphoma. 2012 Dec;53(12):2397-404.

    Outcomes in older adults with acute lymphoblastic leukaemia (ALL): results from the international MRC UKALL XII/ECOG2993 trial. Sive JI, Buck G, Fielding A, Lazarus HM, Litzow MR, Luger S, Marks DI, McMillan A, Moorman AV, Richards SM, Rowe JM, Tallman MS, Goldstone AH. Br J Haematol. 2012 May;157(4):463-71.

  • Professional bodies icon plus

    Member of the British Society for Haematology (BSH)
    Member of the UK Myeloma Forum
    Member of the UK Myeloma Research Alliance

Practice locations

NHS base

University College London Hospitals NHS Trust

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